Expression of P27 mRNA in NPC tissues and NP tissues. A. mRNA expression of p27 was decreased in NPC tissues compared with NP tissues by real-time PCR assay. B. A significant reduction of p27 mRNA expression was indicated in NPC clinical stage III-IV compared with clinical stage I-II. C,D: Significantly differential mRNA expression of p27 was not observed in NPC T3-4 and N2-3 compared with T1-2 and N0-1.