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Table 2 Association of CD44 and CD24 with clinicopathological variables in 69 SGMN patients

From: CD44/CD24 immunophenotypes on clinicopathologic features of salivary glands malignant neoplasms

 

CD44

CD24

+

-

p

+

-

p

Gender

Male

19 (13.0%)

9 (13.0%)

0.330

6 (8.7%)

22 (31.9%)

0.330

 

Female

31 (44.9%)

10 (14.5%)

 

12 (17.4%)

29 (42.0%)

 

Age

≤ 60

30 (43.5%)

11 (15.9%)

0.543

10 (14.5%)

31 (44.9%)

0.453

 

> 60

20 (29.0%)

8 (11.6%)

 

8 (11.6%)

20 (29.0%)

 

Smoking intake

Yes

15 (21.7%)

8 (11.6%)

0.250

5 (7.2%)

18 (26.1%)

0.392

 

No

35 (50.7%)

11 (15.9%)

 

13 (18.8%)

33 (47.8%)

 

Alcohol intake

Yes

9 (13.0%)

5 (7.2%)

0.324

5 (7.2%)

9 (13.0%)

0.275

 

No

41 (59.4%)

14 (20.3%)

 

13 (18.8%)

42 (60.9%)

 

PLSa

Majorb

34 (49.3%)

8 (11.6%)

0.046

11 (15.9%)

31 (44.9%)

0.605

 

Minorc

16 (23.2%)

11 (15.9%)

 

7 (10.1%)

20 (29.0%)

 

Tumor size

T1/T2

28 (40.6%)

14 (20.3%)

0.142

7 (10.1%)

35 (50.7%)

0.027

 

T3/T4

22 (31.9%)

5 (7.2%)

 

11 (15.9%)

16 (23.2%)

 

Clinical Stage

I / II

19 (27.5%)

6 (8.7%)

0.419

2 (2.9%)

23 (33.3%)

0.008

 

III / VI

31 (44.9%)

13 (18.8%)

 

16 (23.2%)

28 (40.6%)

 

Treatment

Surgery

14 (20.3%)

5 (7.2%)

0.572

4 (5.8%)

15 (21.7%)

0.398

 

Sur. Adj. T.d

36 (52.2%)

14 (20.3%)

 

14 (20.3%)

36 (52.2%)

 

Metastasis

No

32 (46.4%)

11 (15.9%)

0.421

10 (14.5%)

33 (47.8%)

0.339

 

Yes

18 (26.1%)

8 (11.6%)

 

8 (11.6%)

18 (26.1%)

 

loco-regional

No

33 (47.8%)

12 (17.4%)

0.519

10 (14.5%)

35 (50.7%)

0.236

recurrence

Yes

17 (24.6%)

7 (10.1%)

 

8 (11.6%)

16 (23.2%)

 

Lymph node

Negative

43 (62.3%)

15 (21.7%)

0.352

10 (14.5%)

48 (69.6%)

0.001

 

Positive

7 (10.1%)

4 (5.8%)

 

8 (11.6%)

3 (4.3%)

 

Death

No

36 (52.2%)

12 (17.4%)

0.332

14 (20.3%)

34 (49.3%)

0.285

 

Yes

14 (20.3%)

7 (10.1%)

 

4 (5.8%)

17 (24.6%)

 

CD24

Negative

36 (52.2%)

15 (21.7%)

   

0.398

 

Positive

14 (20.3%)

4 (5.8%)

    

CD44

Negative

   

4 (5.8%)

15 (21.7%)

0.398

 

Positive

   

14 (20.3%)

36 (52.2%)

 
  1. a PLS: Primary Lesion Site; bMajor: Major Salivary Glands ( Parotid Gland/Submandibular Gland/Sublingual Gland); cMinor; Minor Salivary Glands; dSur. Adj. T.: Surgery with adjuvant therapy. Statistically significant difference (<0.05) by Fisher’s exact test (two variables) or χ2 (three or more variables) tests.