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Table 3 Literature data on sodium and chloride concentrations in saliva of patients with cystic fibrosis (CF)

From: Saliva as a potential tool for cystic fibrosis diagnosis

Researchers

Date

CFG°

CG*

Method

Results

Chernick et al. [13]

1961

12

12

Flame photometry/titration

High level of potassium and low levels of sodium and chloride in patients with CF

Marmar et al. [14]

1966

12

13

Flame photometry/titration

High levels of sodium and chloride in CF patients

Lawson et al. [15]

1967

5

50

Electrode selective

High level of sodium in CF patients

Wiesmann et al. [16]

1970

23

12

Atomic absorption spectrophotometry

No significant differences in sodium level

Fritz et al. [17]

1972

11

0

Unquoted

High levels of chloride and sodium for saliva flow in CF patients

Blomfield et al. [18]

1973

35

28

Atomic absorption spectrophotometry

High levels of chloride and sodium in CF patients

Kollberg et al. [19]

1982

9

11

Flame-emission photometry

High level of sodium in CF patients

Jimenez-Reyes & Sanches-Aguirre [20]

1996

9

9

Atomic absorption spectrophotometry

High level of sodium in CF patients

  1. °CFG: cystic fibrosis group; *CG: control group. Databases of Pubmed, Scielo, Medline and HighWire Stanford University, in the period of 1951 to 2011 were searched. The keywords were: biochemical parameters of saliva and cystic fibrosis.