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Table 2 SXCI (CR ≥ 3) incidences in healthy females of various age ranges and ethnic groups

From: Skewed X-chromosome inactivation in patients with esophageal carcinoma

Authors

Subjects

Numbers examined

Age range (years)

Overall Incidences (%)

SXCI (CR ≥ 3) incidences of healthy females of various age ranges (%)

P- value

0

25- 32

16- 50

35- 50

51- 70

≥60

≥75

71- 96

Lau et al.[8]

Canadian

27

35-50

33

*

*

*

33

*

*

*

*

*

Busque et al.[5]

American

295

0-96☆☆

17

9

16

*

*

*

38

*

*

<0.0001**

Gale et al.[6]

English

174

17-96

38

*

*

22

*

*

*

6

*

< 0.0001*

Tonon et al.[7]

Italian

68

25-32, ≥75

23

*

17

*

*

*

*

45

*

< 0.02☆

Knudsen et al.[11]

Norwegian

80

19-90

65

*

0.034**

Mossner et al.[12]

German with Caucasian background

139

0-40, 41–64, 65-97

34§

*

0.0008**

Racchi et al.[13]

Italian

166

8-94

30

*

23

26

*

*

37

40

*

>0.05**

Gentilini et al.[28]

Italian

148

31-100

38.5

*

<0.0001**

Amos-Landgraf et al.[32]

Finnish American Jewish

1 005

0, >13

25※

*

0.008※※

Present study

Chinese

356

0-96

15

4.3

6.1

7.8

9.4

10.8

27.6

40.6

38.0

0**

  1. * Not mentioned in the study; ** The likelihood ratio test; ※ skewed to the extent of >70:30 or <30:70; ※ ※F test.
  2. §allelic ratios: ≥ 4:1 or 80% predominant expression of one allele.
  3. ☆ The χ2 test; ☆☆ age constitution: neonates (n = 162); younger adults (25–32 y) (n = 67); older adults up to 60 y (n = 66).