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Table 1 Evaluated parameters

From: Long-term analysis to objectify the tumour grading by means of automated microscopic image analysis of the nucleolar organizer regions (AgNORs) in the case of breast carcinoma

Parameters

Definition

n

Conventional parameters

pT

Size of the invasive tumour components

244

pN

Lymph node involvement

235

G

Tumour grading

242

AgNOR parameters

nornbc_m

Mean value of the corrected number of the AgNORs per cell nucleus (the AgNORs lying very close together in the cell nucleus are recorded as a conglomerate and counted accordingly)

242

nor_k1

mean number (percentage) of nuclei contained in 1 AgNOR

244

nor_k2

mean number (percentage) of nuclei contained in 2 AgNORs

244

nor_k4

mean number (percentage) of nuclei contained in 4 AgNORs

244

nor_k5

mean number (percentage) of nuclei contained in 5 AgNORs

244

nor_k6

mean number (percentage) of nuclei contained in 6 AgNORs

244

nor_k7

mean number (percentage) of nuclei contained in 7 AgNORs

244

nor_k8

mean number (percentage) of nuclei contained in 8 AgNORs

244

snar_r_v

Standard deviations of the surface of the single AgNOR in relation to the total surface of the AgNORs per cell nucleus in μm2 per mille

244

center_v

Standard deviation of the position of the AgNORs located in the centre of the cell nucleus

244

cent_r_v

Standard deviation of proportion of AgNORs in a central position

244

bord_r_v

Standard deviation of the proportion of the AgNORs located in the defined, peripheral zone in the cell nucleus

244

locat_v

Position of the NORs

244

mnrat2_m

Mean ratio between largest AgNOR and total AgNOR area size per cell nucleus in per mille

244