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Table 6 Influence of disease characteristics on relapse in patients with nonseminomas

From: Oncological outcomes in patients with stage I testicular seminoma and nonseminoma: pathological risk factors for relapse and feasibility of surveillance after orchiectomy

Variables

No.

Relapse

Univariate analyses

  

n (%)

p

HR

95% CI

Age <40

30

7 (23.3%)

0.92

1.08

0.23-5.21

≥40

10

2 (20.0%)

 

1

Tumor size ≤5 cm

22

5 (22.7%)

0.88

0.90

0.21-3.75

>5 cm

12

3 (25.0%)

 

1

Embryonal carcinoma No

11

4 (36.4%)

0.21

2.31

0.62-8.60

Yes

28

5 (17.9%)

 

1

Choriocarcinoma No

32

8 (25.0%)

0.57

1.83

0.23-14.7

Yes

7

1 (14.3%)

 

1

Teratoma No

17

3 (17.6%)

0.49

0.62

0.15-2.46

Yes

22

6 (27.3%)

 

1

Yalk sac tumor No

19

3 (15.8%)

0.33

0.50

0.13-2.01

Yes

21

6 (28.6%)

 

1

AFP Normal

8

2 (25.0%)

0.93

0.93

0.19-4.49

Elevated

29

7 (24.1%)

 

1

βhCG Normal

13

4 (30.8%)

0.64

1.37

0.37-5.10

Elevated

23

5 (21.7%)

 

1

LDH Normal

20

6 (30.0%)

0.49

1.63

0.41-6.51

Elevated

16

3 (18.8%)

 

1

pT T1

16

3 (18.8%)

0.19

0.39

0.10-1.58

T2-4

15

6 (40.0%)

 

1

Lymphovascular invasion No

16

3 (18.8%)

0.19

0.39

0.10-1.58

Yes

15

6 (40.0%)

 

1

 
  1. LDH, lactate dehydrogenase; AFP, α-fetoprotein, hCGβ, human chorionic gonadotropin β subunit.