Table 3 Univariate and multivariate analysis of hK6 and other clinicopathological characteristics with regard to RFS in advanced gastric cancer
From: Correlation of hK6 expression with tumor recurrence and prognosis in advanced gastric cancer
Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
Variable | HR | 95% CI | P | HR | 95% CI | P |
Gender F/ M | 1.05 | 0.65 -1 .69 | 0.86 | – | – | – |
Age < 60/ ≥60 yr | 1.30 | 0.81- 2.08 | 0.29 | – | – | – |
Tumor site | – | – | 0.58 | – | – | – |
body/fundus | 0.68 | 0.31-1.49 | 0.33 | – | – | – |
antrum/fundus, body | 0.88 | 0.45 -1.71 | 0.70 | – | – | – |
Tumor size < 5/ ≥5 cm | 2.05 | 1.25 - 3.37 | 0.005 | 1.80 | 1.07 – 3.04 | 0.027 |
grade Well/Poorly | 0.88 | 0.40 -1.93 | 0.75 | – | – | – |
T stage | – | – | 0.10 | – | – | – |
T3/T2 | 2.21 | 0.92-5.30 | 0.077 | – | – | 0.58 |
T4/T2,T3 | 2.60 | 1.08 -6.26 | 0.032 | – | – | 0.75 |
N stage N0,N1/N2,N3 | 2.28 | 1.34-3.87 | 0.002 | – | – | 0.83 |
Vascular−/+ | 0.91 | 0.49-1.70 | 0.77 | – | – | – |
Perineural−/+ | 1.27 | 0.71-2.25 | 0.42 | – | – | – |
Margin−/+ | 2.42 | 1.41-4.15 | 0.001 | 2.49 | 1.44– 4.31 | 0.001 |
TNM stage I,II/III,IV | 3.10 | 1.69-5.68 | 0.000 | 2.25 | 1.18 –4.30 | 0.014 |
hK6−/+ | 2.77 | 1.41-5.47 | 0.003 | 2.09 | 1.04 –4. | 230.039 |