Table 4 Association between tSNP genotypes and the risk of glioma
From: RTEL1 tagging SNPs and haplotypes were associated with glioma development
SNP ID | Genotype | No. (frequency) | Logistic regression | ||
|---|---|---|---|---|---|
Case | Control | OR (95% CI) | P value | ||
rs12022378 | CC | 114(18.2) | 87(13.6) | 0.71(0.51-0.99) | 0.0418 |
rs12022378 | CT | 265(42.2) | 288(44.9) | 1.01(0.8-1.29) | 0.9127 |
rs12022378 | TT | 249(39.6) | 267(41.6) | 1(referent) | |
rs12917 | TT | 6(1) | 10(1.6) | 1.7(0.61-4.72) | 0.3011 |
rs12917 | TC | 91(14.5) | 115(17.9) | 1.29(0.96-1.74) | 0.0956 |
rs12917 | CC | 530(84.5) | 519(80.6) | 1(referent) | |
rs12645561 | TT | 43(6.8) | 56(8.7) | 1.26(0.83-1.93) | 0.2784 |
rs12645561 | TC | 251(40) | 241(37.6) | 0.93(0.74-1.18) | 0.5537 |
rs12645561 | CC | 334(53.2) | 344(53.7) | 1(referent) | |
rs7003908 | CC | 31(4.9) | 43(6.7) | 1.44(0.89-2.33) | 0.1387 |
rs7003908 | CA | 201(32) | 217(33.7) | 1.12(0.88-1.42) | 0.3536 |
rs7003908 | AA | 397(63.1) | 383(59.6) | 1(referent) | |
rs6010620 | GG | 75(11.9) | 40(6.2) | 0.46(0.31-0.7) | 0.0002 |
rs6010620 | GA | 261(41.5) | 267(41.5) | 0.89(0.71-1.12) | 0.3212 |
rs6010620 | AA | 293(46.6) | 337(52.3) | 1(referent) | |
rs2297440 | CC | 73(11.6) | 40(6.2) | 0.47(0.31-0.71) | 0.0003 |
rs2297440 | CT | 263(41.8) | 263(40.8) | 0.86(0.68-1.08) | 0.1902 |
rs2297440 | TT | 293(46.6) | 342(53) | 1(referent) | |
rs4809324 | CC | 11(1.8) | 7(1.1) | 0.62(0.24-1.6) | 0.3162 |
rs4809324 | CT | 129(20.5) | 133(20.7) | 1(0.76-1.31) | 0.9901 |
rs4809324 | TT | 488(77.7) | 504(78.3) | 1(referent) | |
rs2992 | AA | 126(20.1) | 117(18.2) | 0.98(0.71-1.35) | 0.9003 |
rs2992 | AG | 292(46.5) | 328(50.9) | 1.19(0.92-1.52) | 0.1822 |
rs2992 | GG | 210(33.4) | 199(30.9) | 1(referent) | |
rs3770502 | AA | 12(1.9) | 15(2.3) | 1.18(0.54-2.54) | 0.6809 |
rs3770502 | AG | 177(28.1) | 161(25) | 0.86(0.67-1.1) | 0.2198 |
rs3770502 | GG | 440(70) | 468(72.7) | 1(referent) | |
rs9288516 | AA | 128(20.4) | 153(23.8) | 1.28(0.93-1.74) | 0.1249 |
rs9288516 | AT | 308(49.1) | 312(48.4) | 1.08(0.84-1.4) | 0.5539 |
rs9288516 | TT | 191(30.5) | 179(27.8) | 1(referent) | |