Table 1 Univariate Analysis of Disease Free Survival – 368 Eligible Patients. In grey: Follow up (2011)
Variable | No. of patients | P value | |
|---|---|---|---|
Age | |||
Mean = 58.7 yr | 0.400 | ||
Menopauses | |||
Yes | 237 (65%) | ||
No | 124 (34%) | ||
Localization | |||
Right breast | 176 (47.8%) | ||
Left breast | 187 (50.8%) | ||
Synchronous bilateral | 5 (01.4%) | ||
Tumor size | |||
Mean = 25 mm | 0.010 | ||
Surgery | |||
Tumorectomy | 212 (57.6%) | ||
Mastectomy | 141 (38.3%) | ||
Biopsy | 15 (04.1%) | ||
Excision quality | |||
Satisfying | 202 (57.2%) | ||
Unsatisfying | 47 (13.3%) | ||
Unspecified | 104 (29.5%) | ||
Histological type | |||
ICC | 297 (80.71%) | ||
ILC | 37 (10.05%) | ||
SBR grade | |||
Grade 1 | 50 (14%) | ||
Grade 2 | 180 (49%) | 0.002 | |
Grade 3 | 137 (37%) | ||
Mitotic index (/1.7mm²) | |||
Mean = 10 mitosis | <0.0001 | ||
Tumor vascular emboli | |||
Yes | 293 (79.6%) | ||
No | 75 (20.4%) | ||
Lymph node metastasis | |||
Yes | 153 (44%) | <0.0001 | |
No | 195 (56%) | ||
Hormone receptor status (at least 1) | |||
Yes | 265 (73%) | 0.030 | |
No | 98 (27%) | ||
Visceral or lymph node (other than axillary) metastasis | |||
Yes | 136 (37%) | ||
No | 232 (63%) | ||
Local recurrence | |||
Yes | 66 (18%) | ||
No | 302 (82%) | ||
Oncological event (Metastasis and/or local recurrence) | |||
Yes | 157 (42.5%) | ||
No | 211 (57.5%) | ||
Death | |||
Yes | 90 (24.46%) | ||
No | 278 (75.54%) | ||