Figure 3
Photomicrograph of the prepuce squamous cell carcinoma in the dog. Hematoxylin/eosin staining showing a non-metastasizing well-differentiated prepuce squamous cell carcinoma. The neoplastic epithelium demonstrates progressive differentiation from a peripheral basal layer with centripetal keratinization. Numerous keratin pearls are present and cellular atypia in all layers of the epidermis, epidermal tissue lying free in the thickness connective tissue (subepidermal) HE. ×40.