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Table 4 Sequence variants in the PDGFR-α, EGFR, KRAS and KIT genes

From: KRAS, EGFR, PDGFR-α, KIT and COX-2 status in carcinoma showing thymus-like elements (CASTLE)

Gene

Exon

Nucleotide alt.

Amino acid subst.

No.

Interpretation

dbSNP

PDGFR-α

10

-

-

4

wild type

-

 

12

c.A1701G

p.P567P

4

SNP

rs1873778

 

14

-

-

4

wild type

-

 

18

-

-

4

wild type

-

EGFR

18

-

-

4

wild type

-

 

19

-

-

4

wild type

-

 

20

c.G2361A

p.Q787Q

3

SNP

rs1050171

 

20

-

-

1

wild type

-

 

21

-

-

4

wild type

-

KRAS

2

-

-

4

wild type

-

 

3

-

-

4

wild type

-

KIT

9

-

-

4

wild type

-

 

11

-

-

4

wild type

-

 

13

-

-

4

wild type

-

 

17

-

-

4

wild type

-

  1. No. Number of patients; dbSNPhttp://www.ncbi.nlm.nih.gov/SNP/; SNP single nucleotide polymorphism; Nucleotide alt. Nucleotide alteration; Amino acid subst. Amino acid substitution.