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Table 4 Sequence variants in the PDGFR-α, EGFR, KRAS and KIT genes

From: KRAS, EGFR, PDGFR-α, KIT and COX-2 status in carcinoma showing thymus-like elements (CASTLE)

Gene Exon Nucleotide alt. Amino acid subst. No. Interpretation dbSNP
PDGFR-α 10 - - 4 wild type -
  12 c.A1701G p.P567P 4 SNP rs1873778
  14 - - 4 wild type -
  18 - - 4 wild type -
EGFR 18 - - 4 wild type -
  19 - - 4 wild type -
  20 c.G2361A p.Q787Q 3 SNP rs1050171
  20 - - 1 wild type -
  21 - - 4 wild type -
KRAS 2 - - 4 wild type -
  3 - - 4 wild type -
KIT 9 - - 4 wild type -
  11 - - 4 wild type -
  13 - - 4 wild type -
  17 - - 4 wild type -
  1. No. Number of patients; dbSNPhttp://www.ncbi.nlm.nih.gov/SNP/; SNP single nucleotide polymorphism; Nucleotide alt. Nucleotide alteration; Amino acid subst. Amino acid substitution.