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Table 1 Correlation between TRPS1 expression and the clinicopathologic characteristics of breast cancer patients

From: Association of TRPS1 gene with different EMT markers in ERα-positive and ERα-negative breast cancer

Characteristics n TRPS1 expression P value Spearman Value (r) P value
Negative Positive Correlation
Age(y)        
≤50 70 26 44 0.017   −0.179 0.016
>50 110 61 49     
Grade        
I 11 5 6 0.903    
II 124 59 65     
III 45 23 22     
Pathological stage        
I 49 23 26 0.646    
II 85 44 41     
III 46 20 26     
Tumor size        
<2 60 26 34 0.343    
≥2 120 61 59     
Lymph node metastasis        
Negative 94 48 46 0.443    
Positive 86 39 47     
Expression of Ki67        
≤25% 62 20 42 0.002   −0.233 0.002
>25% 118 67 51     
Expression of P53        
Negative 72 40 32 0.113    
Positive 108 47 61     
ERα        
Negative 75 51 24 <0.001   0.333 <0.001
Positive 105 36 69     
PR        
Negative 75 50 25 <0.001   0.31 <0.001
Positive 105 37 68     
HER-2        
Negative 124 53 71 0.025   −0.166 0.025
Positive 56 34 22     
E-cadherin        
Negative 33 24 9 0.002   0.231 0.002
Positive 147 63 84     
Slug        
Negative 170 86 84 0.019   0.186 0.012
Positive 10 1 9     
Vimentin        
Negative 165 84 81 0.022   0.171 0.022
Positive 15 3 12     
SMA        
Negative 169 85 84 0.039   0.154 0.039
Positive 11 2 9     
β-catenin        
Negative 67 42 25 0.003   0.221 0.003
Positive 113 45 68     
ERβ        
≤2 92 55 37 0.001   0.242 0.001
>2 87 31 56     
IMP3        
Negative 157 77 80 0.618    
Positive 23 10 13