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Table 1 Correlation between TRPS1 expression and the clinicopathologic characteristics of breast cancer patients

From: Association of TRPS1 gene with different EMT markers in ERα-positive and ERα-negative breast cancer

Characteristics

n

TRPS1 expression

P value

Spearman

Value (r)

P value

Negative

Positive

Correlation

Age(y)

       

≤50

70

26

44

0.017

 

−0.179

0.016

>50

110

61

49

    

Grade

       

I

11

5

6

0.903

   

II

124

59

65

    

III

45

23

22

    

Pathological stage

       

I

49

23

26

0.646

   

II

85

44

41

    

III

46

20

26

    

Tumor size

       

<2

60

26

34

0.343

   

≥2

120

61

59

    

Lymph node metastasis

       

Negative

94

48

46

0.443

   

Positive

86

39

47

    

Expression of Ki67

       

≤25%

62

20

42

0.002

 

−0.233

0.002

>25%

118

67

51

    

Expression of P53

       

Negative

72

40

32

0.113

   

Positive

108

47

61

    

ERα

       

Negative

75

51

24

<0.001

 

0.333

<0.001

Positive

105

36

69

    

PR

       

Negative

75

50

25

<0.001

 

0.31

<0.001

Positive

105

37

68

    

HER-2

       

Negative

124

53

71

0.025

 

−0.166

0.025

Positive

56

34

22

    

E-cadherin

       

Negative

33

24

9

0.002

 

0.231

0.002

Positive

147

63

84

    

Slug

       

Negative

170

86

84

0.019

 

0.186

0.012

Positive

10

1

9

    

Vimentin

       

Negative

165

84

81

0.022

 

0.171

0.022

Positive

15

3

12

    

SMA

       

Negative

169

85

84

0.039

 

0.154

0.039

Positive

11

2

9

    

β-catenin

       

Negative

67

42

25

0.003

 

0.221

0.003

Positive

113

45

68

    

ERβ

       

≤2

92

55

37

0.001

 

0.242

0.001

>2

87

31

56

    

IMP3

       

Negative

157

77

80

0.618

   

Positive

23

10

13