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Table 4 The FISH and IHC detection of EGFR signals in CNS small cell tumors

From: A prognostic analysis of pediatrics central nervous system small cell tumors: evaluation of EGFR family gene amplification and overexpression

 

CNS small cell tumors

The number of patients (median survival time)

  

FISH

IHC

MB (34)

+

-

+

10 (10.75 ± 4.1)

4 (29.51 ± 2.33)

-

9 (21.14 ± 3.29)

11 (59.18 ± 10.21)

 

FISH

GBM (15)

+

-

+

6 (2.5 ± 1.1)

2 (4)

-

1 (10)

6 (12.27 ± 2.21)

 

FISH

PNET (8)

+

-

+

3 (3.5 ± 2.1)

1 (11)

-

1 (5)

3 (all alive > 54)

  1. Note: FISH: Fluorescence of in situ hybridization; IHC: immunohistochemistry.