Lack of association between a functional polymorphism (rs1800796) in the interleukin-6 gene promoter and lung cancer

Table 1 Characteristics of the included studies of the association between IL-6 rs1800796 variant and lung cancer

Study	Country	Ethnicity	Sample size		Genotype frequency in cases			Genotype frequency in controls			P _HWE
Study	Country	Ethnicity	Cases	Controls	GG	GC	CC	GG	GC	CC	P _HWE
Su, 2010 [6]	China	East Asian	363	370	193	156	14	233	117	20	0.30
Lim, 2011 [7]	Singapore	East Asian	298	718	163	123	12	449	231	38	0.25
Bai, 2013 [8]	China	East Asian	193	210	86	89	18	125	69	16	0.15
Chen, 2013 (discovery group) [9]	China	East Asian	622	614	349	229	44	309	252	53	0.87
Chen, 2013 (validation group) [9]	China	East Asian	615	638	333	245	37	321	263	54	0.99
Liang, 2013 [10]	China	East Asian	138	138	100	29	9	105	30	3	0.62
Kiyohara, 2014 [11]	Japan	East Asian	462	379	259	175	28	250	116	13	0.92

ISSN: 1746-1596