Table 2 Cases of urinary bladder IMT
No of case | Sex | Age | Size | Clinical symptoms | Immunophenotype of tumor cells | First diagnosis | FISH | Follow up | No of (art.) |
|---|---|---|---|---|---|---|---|---|---|
1 | M | 13 | 6 × 3 cm | Weight loss, hematuria, abdominal pain | CK(+), VIM(+), ALK-1(+) | Proliferation of fusiform myoepithelial cells | Nd | 2 months without recurrence | 5 |
2 | F | 27 | 6.4 × 4.5 × 3,8 cm | Fever, diffuse myalgia, weight loss, anemia, | CK(-), SMA(+), MyoD1(-), ALK-1(+) | IMT | Nd | 2 months without recurrence | 6 |
3 | F | 35 | 7.5 × 4.5 cm | Duration, gross hematuria, bacteruria | CK(-), VIM(+), S-100(-), CD68(+) | Glandular cystitis | Nd | 1 year without recurrence | 7 |
4 | F | 36 | 2.4 × 2.3 × 2.2 cm | Hematuria, abdominal pain | CK8/18/19 focally(+), S100(-),ALK1(+), MyoD1(-), CD117(-) | Low grade leiomyosarcoma | Nd | 3 years without recurrence | 8 |
5 | M | 58 | 3 cm | hematuria, | CK(-), VIM(+) | Postoperative spindle cell nodule (PSCN) but excluded because of absence of previous surgery | Nd | Nd | 9 |
6 | F | 27 | 6 × 5 cm | Hematuria, dots in urine, burning micturition, weakness, abdominal pain | CK 20(-), SMA(+), VIM(+), ALK-1(+), DES(-), CD117(-) | IMT | Nd | 15 months without recurrence | 10 |
7 | M | 30 | Nd | CK(-),SMA(+), VIM(+), ALK-1(+), DES(+), Myogenin(-) | IMT | Nd | Nd | 11 | |
8 | F | 52 | 3 cm | Painful urination | CK(+), ALK-1(+) | Sarcomatoid carcinoma | Nd | 1 year without recurrence | 12 |
9 | F | 8 | 4.5 cm | Hematuria, abdominal pain | SMA(+), VIM(+), ALK-1(+), DES(+), Myoglobin(-), CD34 (-), S-100 (-) | IMT | Nd | 13 months without recurrence | 13 |