Table 1 Immunohistochemistry in the differential diagnosis of PEComa tumors
From: Primary perivascular epithelioid cell tumor of the liver: new case report and literature review
PEComa | Gastrointestinal stromal tumors | Carcinoma | Melanoma | Paraganglioma | |
|---|---|---|---|---|---|
SMA | positive | variable | |||
H-caldesmon | positive | ||||
Desmine | positive | variable | |||
HMB-45 | positive | positive | |||
Melan-A | positive | positive | |||
S-100 protein | rarely | variable | positive | positive | |
Chromogranin A | negative | rarely | positive | ||
Synaptophysin | negative | rarely | positive | ||
CK | negative | negative | positive | negative | |
EMA | negative | positive | negative | ||
CD117 | negative | positive | |||
CD34 | negative | positive |