Skip to main content

Table 1 Clinicopathological features and EGFR gene status of the 44 adrenocortical tumors

From: Adrenal cortical neoplasms: a study of clinicopathological features related to epidermal growth factor receptor gene status

  Malignant (n = 22) Benign (n = 22) p value
Age (yrs)
 Mean 43.4 47.4 0.364
 Range 2–75 34–69
Sex
 Males 13 9 0.228
 Females 9 13
Hormonal function
 Functioning 8 7 0.498
 Non-functioning 14 15
Tumor location
 Right 14 13 0.757
 Left 8 9
Tumor size (cm)
 Mean 12.3 2.9 <0.001*
 Range 3-24 0.8-5.5
Tumor weight (g)
 Mean 847.0 10.6 <0.001*
 Range 12-3250 1-42
EGFR copy number
 Positive 11 0 <0.001*,†
 Negative 11 22
EGFR IHC
 Positive 14 7 0.035*
 Negative 8 15  
  1. EGFR, epidermal growth factor receptor; IHC, immunohistochemistry.
  2. *Statistically significant.
  3. Fisher’s exact test (two-tailed).