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Table 1 Clinicopathological features and EGFR gene status of the 44 adrenocortical tumors

From: Adrenal cortical neoplasms: a study of clinicopathological features related to epidermal growth factor receptor gene status

 

Malignant (n = 22)

Benign (n = 22)

p value

Age (yrs)

 Mean

43.4

47.4

0.364

 Range

2–75

34–69

Sex

 Males

13

9

0.228

 Females

9

13

Hormonal function

 Functioning

8

7

0.498

 Non-functioning

14

15

Tumor location

 Right

14

13

0.757

 Left

8

9

Tumor size (cm)

 Mean

12.3

2.9

<0.001*

 Range

3-24

0.8-5.5

Tumor weight (g)

 Mean

847.0

10.6

<0.001*

 Range

12-3250

1-42

EGFR copy number

 Positive

11

0

<0.001*,†

 Negative

11

22

EGFR IHC

 Positive

14

7

0.035*

 Negative

8

15

 
  1. EGFR, epidermal growth factor receptor; IHC, immunohistochemistry.
  2. *Statistically significant.
  3. Fisher’s exact test (two-tailed).