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Table 3 The correlation between GCS and the histopathological variables in 143 cases of invasive breast cancer

From: Expression of glucosylceramide synthase in invasive ductal breast cancer may be correlated with high estrogen receptor status and low HER-2 status

  

GCS (+)(104,72.7%)

GCS(-) (39, 27.3%)

P-value

Age

<35

3

5

0.035*

 

≥35

101

34

 

Tumor stage

T1-2

50

22

0.453

 

T3-4

54

17

 

Nodal stage

N0

27

15

0.375

 

N1-x

23

14

 

Histologic grade

Grade I

15

1

0.045

 

Grade II-Ш

89

38

 

ER

Positive

73

31

0.017

 

Negative

19

20

 

PR

Positive

69

22

0.271

 

Negative

35

17

 

HER-2

Positive

22

17

0.007*

 

Negative

82

22

 

Ki67

<14%

23

7

0.652

 

≥14%

81

32

 
  1. *P < 0.05.
  2. ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor-2.
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Diagnostic Pathology

ISSN: 1746-1596

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