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Table 3 The correlation between GCS and the histopathological variables in 143 cases of invasive breast cancer

From: Expression of glucosylceramide synthase in invasive ductal breast cancer may be correlated with high estrogen receptor status and low HER-2 status

   GCS (+)(104,72.7%) GCS(-) (39, 27.3%) P-value
Age <35 3 5 0.035*
  ≥35 101 34  
Tumor stage T1-2 50 22 0.453
  T3-4 54 17  
Nodal stage N0 27 15 0.375
  N1-x 23 14  
Histologic grade Grade I 15 1 0.045
  Grade II-Ш 89 38  
ER Positive 73 31 0.017
  Negative 19 20  
PR Positive 69 22 0.271
  Negative 35 17  
HER-2 Positive 22 17 0.007*
  Negative 82 22  
Ki67 <14% 23 7 0.652
  ≥14% 81 32  
  1. *P < 0.05.
  2. ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor-2.