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Table 4 Copy number variations of mtDNA in early-stage laryngeal cancer — univariate associations with clinicopathological characteristics

From: Low copy number of mitochondrial DNA (mtDNA) predicts worse prognosis in early-stage laryngeal cancer patients

Characteristics

Copy number <4.02

 

Copy number >5.42

 

OR*(95% CI)

P

OR*(95% CI)

P

Age

1.00 (0.94-1.06)

0.93

1.03 (0.98-1.09)

0.29

Tumor invasion1

1.25 (0.39-4.04)

0.71

0.48 (0.15-1.52)

0.21

Smoking history2

0.25 (0.05-1.31)

0.10

0.17 (0.04-0.85)

0.03

Survival status3

1.09 (0.34-3.54)

0.88

0.54 (0.17-1.69)

0.29

  1. *OR: odds ratio with 95% confidence interval; 1Tumor invasion (T1; T2; T3; T4); 2Smoking history (at least 10 pack-years); 3Survival status (Alive vs. Dead); The cases with 4.02-5.42 mtDNA copies were used as reference.