Figure 1
From: Poorly differentiated component in gastric pinch biopsies predicts submucosal invasion
Representative photomicrographs of pre-treatment biopsies of gastric carcinoma with submucosal invasion. Sheets of poorly differentiated neoplastic cells within the lamina propria (a); intraluminal amorphous and eosinophilic necrotic cell debris in the lumens of atypical glands (b); small wisps of smooth muscle fibers entrapped within adenocarcinoma (c); papillary structures with a fibrovascular core (d); tumor cribriforming (e); and microscopic ulcer with necrotic exudates (f).