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Table 3 Staining pattern of glomeruli and tubules with beta dystroglycan in MCD, FSGS, IGAN and MGN

From: Podocin and Beta Dystroglycan expression to study Podocyte-Podocyte and basement membrane matrix connections in adult protienuric states

Histological parameters

Degree

Groups

P value

 

MCD

FSGS

IgAN

MGN

Glomerular staining of

Absent

n(%)

4(18.1%)

4(19.0%)

4(20.0%)

1(4.0%)

0.975 NS

beta-dystroglycan

Mild

n(%)

4(18.1%)

3(14.2%)

6(30.0%)

4(16.0%)

 

Moderate

n(%)

10(45.4%)

10(47.6%)

7(35.0%)

7(28.0%)

 

Intense

n(%)

4(18.1%)

4(19.0%)

3(15.0%)

13(52.0%)

Tubules (PCT) staining pattern of

Absent

n(%)

8(36.3%)

5(23.8%)

15(75.00%

11(44.0%)

0.009 *

beta dystroglycan

Mild

n(%)

0

2(9.5%)

0

3(12.0%)

 

Moderate

n(%)

4(18.1%)

9(42.8%)

5(25.00%)

8(32.0%)

 

Intense

n(%)

10(45.4%)

5(23.8%)

0

3(12.0%)

Tubules (DCT) staining pattern of

Absent

n(%)

2(9.0%)

2(9.5)

7(35.0%)

3(12.0%)

0.92 NS

beta dystroglycan

Mild

n(%)

0

0

0

2(8.0%)

 

Moderate

n(%)

6(27.2%)

5(23.8%)

7(35.0%)

7(28.0%)

 

Intense

n(%)

14(63.6%)

14(66.6%)

6(30.0%)

13(52.0%)

% Tubular staining

<30%

n(%)

6(27.27%)

5(23.8%)

10(50.0%)

6(24.0%)

<0.001*

30-60%

n(%)

10(45.4%)

6(28.5%)

0

3(12.0%)

>60%

n(%)

6(27.2%)

10(47.6%)

10(50.0%)

16(64.0%)

  1. Note; MCD-Minimal change disease, FSGS-focal segmental glomerulosclerosis, IgA N-IgA nephropathy, MGN-Membranous glomerulonephritis, NS-not significant, PCT-proximal convoluted tubules, DCT-distal convoluted tubules, *- statistically significant.