Table 2 Weiss criteria with Aubert’s modifications for distinguishing adrenal cortical carcinoma from adenoma[17]
Weiss criteria | Our case (“+” = presence; “-” = absence) |
|---|---|
Nuclear grade by Fuhrman (III/IV) | + |
MI (mitotic index) >5/50 HPF | + |
Atypical mitoses | + |
Clear cells <25% | + |
Diffuse architecture >33% | + |
Necrosis | + |
Venous invasion | + |
Sinusoid invasion | + |
Capsular invasion | + |
Total Weiss score | 9 |