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Table 1 Correlations of PAK2 and pSer20PAK2 expression with the clinicopathological features of primary gastric cancer

From: Activation of P21-activated protein kinase 2 is an independent prognostic predictor for patients with gastric cancer

Features

No. of cases

PAK2 expression

P

pSer20PAK2

P

High (%)

Low (%)

High (%)

Low (%)

Age (years)

82

65.32 ± 11.06

64.59 ± 11.88

NS

65.17 ± 11.29

64.99 ± 11.81

NS

Gender

       

 Male

56

42 (75.00)

14 (25.00)

NS

47 (83.93)

9 (16.07)

NS

 Female

26

20 (76.92)

6 (23.08)

22 (84.62)

4 (15.38)

Histopathological type

       

 Intestina type

       

 pap

3

2 (66.67)

1 (33.33)

NS

2 (66.67)

1 (33.33)

NS

 tub1

19

15 (78.95)

4 (21.05)

16 (84.21)

3 (15.79)

 tub2

22

16 (72.73)

6 (27.27)

18 (81.82)

4 (18.18)

Diffuse type

       

 por1

12

8 (66.67)

4 (33.33)

NS

10 (83.33)

2 (16.67)

NS

 por2

26

21 (80.77)

5 (19.23)

23 (88.46)

3 (11.54)

Tumor depth (pT)

       

 pT1 ~ pT2

62

42 (67.74)

20 (32.26)

0.022

49 (79.03)

13 (20.97)

0.036

 pT3 ~ pT4

20

20 (100.00)

0 (0)

20 (100.00)

0 (0)

Lymph node metastasis (pN)

       

 pN0 ~ pN1

66

46 (69.70)

20 (30.30)

0.022

53 (80.30)

13 (19.70)

0.036

 pN2 ~ pN3

16

16 (100.00)

0 (0)

16 (100.00)

0 (0)

Distant metastasis (pM)

       

 pM0

76

56 (73.68)

20 (26.32)

0.025

63 (82.89)

13 (17.11)

0.038

 pM1

6

6 (100.00)

0 (0)

6 (100.00)

0 (0)

pStage

       

 I ~ II

59

39 (66.10)

20 (33.90)

0.018

46 (77.97)

13 (33.90)

0.031

 III ~ IV

23

23 (100.00)

0 (0)

23 (100.00)

0 (0)

Lymphatic invasion

       

 Negative

35

26 (74.29)

9 (25.71)

NS

29 (82.86)

6 (17.14)

NS

 Positive

47

36 (74.60)

11 (25.40)

40 (85.11)

7 (14.89)

Venous invasion

       

 Negative

58

42 (72.41)

16 (17.59)

NS

49 (84.48)

9 (15.52)

NS

 Positive

24

20 (83.33)

4 (16.67)

20 (83.33)

4 (16.67)

Hematogenous recurrence

       

 Negative

72

55 (76.39)

17 (23.61)

NS

61 (84.72)

11 (15.28)

NS

 Positive

10

7 (70.00)

3 (30.00)

8 (80.00)

2 (20.00)

Peritoneal recurrence

       

 Negative

72

55 (76.39)

17 (23.61)

NS

61 (84.72)

11 (15.28)

NS

 Positive

10

7 (70.00)

3 (30.00)

8 (80.00)

2 (20.00)

  1. Note: ‘NS’ refers to ‘no significant’.