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Figure 2 | Diagnostic Pathology

Figure 2

From: A new in situ hybridization and immunohistochemistry with a novel antibody to detect small T-antigen expressions of Merkel cell polyomavirus (MCPyV)

Figure 2

MCPyV-pseudonegative [CM2B4 (−) and MCPyV-DNA (+)] and -pseudopositive [CM2B4 (+) and MCPyV-DNA (−)] MCCs. MCC UK11 case (A) was negative for MCPyV-LT (CM2B4) (C) despite the presence of MCPyV-DNAs (LT-DNA; 3.81 copies/cell) and was positive for MCPyV-ST immunoreactivity (ST-1) (E) and -ST mRNA expression by ISH (G). CM2B4-positive MCC64 (B) had no MCPyV-DNAs and showed no expression of ST-1 (F) and ST mRNA (H). A and B, H and E stain; A through H, original magnification × 400.

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Diagnostic Pathology

ISSN: 1746-1596

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