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Figure 2 | Diagnostic Pathology

Figure 2

From: Whole DNA methylome profiling in lung cancer cells before and after epithelial-to-mesenchymal transition

Figure 2

Global properties of DNA methylation in the A549 cell line. (a) The distribution of all CCGG sites and those with more than 30 reads. CCGG sites with 30+ reads are similarly distributed with all CCGG sites. (b) The distribution of CCGG methylation levels from the perspective of genes (hollow dots). The black line shows the moving average methylation level. (c) The CCGG sites with 30+ reads were mapped to CGIs and CGI shores. More than half of the CCGG sites are located in CGIs or CGI shores. (d) Overall methylation levels of the CCGG sites located in the respective regions.

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Diagnostic Pathology

ISSN: 1746-1596

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