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Figure 3 | Diagnostic Pathology

Figure 3

From: Amplification of Mdmx and overexpression of MDM2 contribute to mammary carcinogenesis by substituting for p53 mutations

Figure 3

Immunohistochemical staining for TP53,MDMx and MDM2 in primary breast cancer. (A) p53 accumulation with diffuse strong nuclear staining in the tumor cells (×400). (B) MDMx overexpression with diffuse and strong nuclear staining (×400) in the tumor cells with Mdmx amplification. (C) MDM2 overexpression with nuclear and cytoplasmic staining in the tumor cells (×400).

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