Figure 3From: Amplification of Mdmx and overexpression of MDM2 contribute to mammary carcinogenesis by substituting for p53 mutationsImmunohistochemical staining for TP53,MDMx and MDM2 in primary breast cancer. (A) p53 accumulation with diffuse strong nuclear staining in the tumor cells (×400). (B) MDMx overexpression with diffuse and strong nuclear staining (×400) in the tumor cells with Mdmx amplification. (C) MDM2 overexpression with nuclear and cytoplasmic staining in the tumor cells (×400).Back to article page