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Table 1 Significant associations of HMG-CoA reductase expression with clinicopathological characteristics and investigative factors

From: HMG-CoA reductase expression in primary colorectal cancer correlates with favourable clinicopathological characteristics and an improved clinical outcome

 

HMG-CoA reductase expression

 

Factor

Negative

Positive

P-value

N(%)

61 (11.4)

474 (88.6)

M stage

   

0

41(68.3)

395 (84.4)

0.002

1

19 (31.7)

73 (15.6)

 

Missing

1

6

 

Vascular invasion

   

No

11 (32.4)

142 (50.7)

0.043

Yes

23 (67.6)

138 (49.3)

 

Missing

17

194

 

Microsatellite instability

   

MSS

52(94.5)

371 (83.6)

0.033

MSI

3 (5.5)

73 (16.4)

 

Missing

6

30

 

Cyclin D1 expression

   

Negative

22 (37.3)

80 (17.7)

<0.001

Positive

37 (62.7)

371 (82.3)

 

Missing

2

23

 

p21 expression

   

Negative

20 (33.9)

53 (11.8)

<0.001

Positive

39 (66.1)

396 (88.2)

 

missing

2

25

 
  1. The categories marked as missing were not included in the analysis.