Table 2 Cox proportional hazards analysis of colorectal cancer specific survival according to HMG-CoA reductase expression
Full cohort | Stage I-II disease | Stage I-II disease | ||||
|---|---|---|---|---|---|---|
HR (95%CI) | n (events) | HR (95%CI) | n (events) | HR (95%CI) | n (events) | |
Unadjusted | Unadjusted | Unadjusted | ||||
HMGCR pos | 1.00 | 474 (153) | 1,00 | 243 (33) | 1,00 | 208 (116) |
HMGCR neg | 1.79 (1-20-2.66) | 61 (29) | 1.56 (0.61-4.01) | 25 (5) | 1.71 (1.09-2.68) | 31 (23) |
Adjusted | Adjusted | Adjusted | ||||
HMGCR pos | 1.00 | 406 (126) | 1.00 | 227 (30) | 1.00 | 179 (96) |
HMGCR neg | 0.85 (0.51-1.41) | 45 (19) | 1.23 (0.41-3.70) | 23 (4) | 0.82 (0.46-1.46) | 22 (15) |