CD44v/CD44s expression patterns are associated with the survival of pancreatic carcinoma patients

Diagnostic Pathology

Table 2 Univariate analysis of prognostic factors in pancreatic adenocarcinoma (n = 101)

Variables	n	Median survival time (months)	2-year survival rate (%)	P-value
Age (years)				0.545
< 65	53	12	20.0
≥65	22	13	20.2
Gender				0.793
Female	16	10	12.5
Male	59	12	22.5
Tumor size (cm)				0.230
≤2	28	12	28.0
>2	47	11	15.9
pN				0.002
Negative	39	14	28.2
Positive	36	10	10.8
Pv				0.045
Negative	55	12	26.1
Positive	20	10	5.0
Hepatic metastases				0.000
Negative	68	12	22.3
Positive	7	6	0
Differentiation				0.989
Poor	21	11	25.8
Moderate	49	12	17.7
Well	5	10	20.0
pStage (UICC)				0.000
I	24	16	33.3
II	44	11	15.9
III,IV	7	6	0
CD44v6 expression				0.010
Negative	35	14	28.5
Positive	40	10	13.0
CD44v9 expression				0.047
Negative	37	12	27.0
Positive	38	10	13.7
CD44s expression				0.032
Negative	40	10	12.5
Positive	35	14	29.6
CD44v6,v9 expression				0.014
Negative	40	13	27.3
Positive	35	10	12.0
CD44v6,s expression				0.000
Negative	53	13	29.0
Positive	22	7	0
CD 44v9,s expression				0.000
Negative	53	13	29.0
Positive	22	7	0

The bold values indicate P-values less than 0.05. pN pathological node stage, pV pathological vessel status, pStage TNM stage (UICC), s CD44s.

ISSN: 1746-1596