CD44v/CD44s expression patterns are associated with the survival of pancreatic carcinoma patients

Diagnostic Pathology

Table 3 Multivariate analysis of the prognostic factors associated with survival in pancreatic adenocarcinoma (n = 101)

Independent factors	Univariate P	Multivariate P	Hazard ratio	95% Confidence interval
Pn (Neg/Pos)	0.002	0.002	2.313	1.376-3.889
pv (Neg/Pos)	0.045	0.370	1.342	0.705-2.557
Hepatic metastases (Neg/Pos)	0.000	0.051	2.558	0.998-6.555
pStage (I/II/III, IV)	0.000	0.925	1.041	0.450-2.407
CD44v6 expression (Neg/Pos)	0.010	0.281	1.869	0.600-5.824
CD44v9 expression (Neg/Pos)	0.047	0.718	0.748	0.155-3.603
CD44s expression (Neg/Pos)	0.032	1.000	1.000	0.437-2.287
CD44v6,v9 expression (Neg/Pos)	0.014	0.809	0.809	0.146-4.486
CD44v6,s expression (Neg/Pos)	0.000	0.003	2.602	1.390-4.870
CD44v9,s expression (Neg/Pos)	0.000	0.810	0.808	0.142-4.587

The bold values indicate P-values less than 0.05 in multivariate analysis, pN pathological node stage, pV pathological vessel status, pStage TNM stage (UICC), s CD44s, Neg negative, Pos positive.

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