Skip to main content

Table 4 Correlation between miR-143 expression and cervical SCC clinical pathological features

From: Down regulation of miR-143 is related with tumor size, lymph node metastasis and HPV16 infection in cervical squamous cancer

Clinical characters

Cases (n)

miR-143 expression

Z

P

Cervical SCC

  

−2.180

0.029*

No

20

1.000 (0.241-1.878)

  

Yes

77

0.280 (0.059-1.050)

  

Age (years old)

  

−1.236

0.217

≤ 50

41

0.259 (0.143-0.707)

  

> 50

36

0.337 (0.167-1.092)

  

Clinical Stage

  

2.673

0.263

I

16

0.387 (0.176-1.258)

  

II

43

0.268 (0.131-0.698)

  

III-IV

18

0.287 (0.155-0.905)

  

Pathological Grade

  

−1.142

0.253

Well differentiation

27

0.320 (0.198-0.859)

  

Moderate and poor differentiation

50

0.258 (0.118-1.052)

  

Lymph node metastasis

  

−2.293

0.022*

No

43

0.578 (0.209-1.384)

  

Yes

16

0.175 (0.103-0.544)

  

Tumor diameter

  

−2.705

0.007*

≤ 4 cm (smaller tumor)

54

0.345 (0.112-1.490)

  

> 4 cm (larger tumor)

23

0.125 (0.103-0.459)

  

LVSI

  

−0.567

0.571

No

46

0.294 (0.159-1.075)

  

Yes

13

0.607 (0.293-1.501)

  

HPV infection

  

9.050

0.011*

HPV negative

17

1.053 (0.289-1.412)

  

HPV16 infection (single or multiple)

32

0.230 (0.105-0.496)

−2.647

0.008*

Other genotype HPV infection

28

0.524 (0.109-1.233)

−1.651

0.099

  1. Note: *P < 0.05. in comparison with HPV negative group.
  2. SCC, squamous cell carcinoma; LVSI, lymph vascular space invasion.