Clinical characters | Cases (n) | miR-143 expression | Z | P |
---|---|---|---|---|
Cervical SCC | −2.180 | 0.029* | ||
No | 20 | 1.000 (0.241-1.878) | ||
Yes | 77 | 0.280 (0.059-1.050) | ||
Age (years old) | −1.236 | 0.217 | ||
≤ 50 | 41 | 0.259 (0.143-0.707) | ||
> 50 | 36 | 0.337 (0.167-1.092) | ||
Clinical Stage | 2.673 | 0.263 | ||
I | 16 | 0.387 (0.176-1.258) | ||
II | 43 | 0.268 (0.131-0.698) | ||
III-IV | 18 | 0.287 (0.155-0.905) | ||
Pathological Grade | −1.142 | 0.253 | ||
Well differentiation | 27 | 0.320 (0.198-0.859) | ||
Moderate and poor differentiation | 50 | 0.258 (0.118-1.052) | ||
Lymph node metastasis | −2.293 | 0.022* | ||
No | 43 | 0.578 (0.209-1.384) | ||
Yes | 16 | 0.175 (0.103-0.544) | ||
Tumor diameter | −2.705 | 0.007* | ||
≤ 4 cm (smaller tumor) | 54 | 0.345 (0.112-1.490) | ||
> 4 cm (larger tumor) | 23 | 0.125 (0.103-0.459) | ||
LVSI | −0.567 | 0.571 | ||
No | 46 | 0.294 (0.159-1.075) | ||
Yes | 13 | 0.607 (0.293-1.501) | ||
HPV infection | 9.050 | 0.011* | ||
HPV negative | 17 | 1.053 (0.289-1.412) | ||
HPV16 infection (single or multiple)△ | 32 | 0.230 (0.105-0.496) | −2.647 | 0.008* |
Other genotype HPV infection△ | 28 | 0.524 (0.109-1.233) | −1.651 | 0.099 |