Figure 7

Correlation of nuclear morphology and caspase-3 expression. The caspase-3 expression of each individual cell was measured and compared with the measurements of nuclear morphology to explore whether nuclear shape is correlated with apoptosis. Caspase-3 expression of each individual cell correlated significantly with a morphological indicator defined as the circumference of the nucleus divided by form factor (A), nuclear area factor (nuclear area divided by form factor) (B), nuclear circumference (C), nuclear area (D), nuclear form factor (E) and the product of nuclear area and form factor (F).