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Table 1 Scale for quality assessment

From: Current evidences on XPC polymorphisms and gastric cancer susceptibility: a meta-analysis

Criteria

Score

Representativeness of cases

 

 Selected from cancer registry or multiple cancer center sites

2

 Selected from oncology department or cancer institute

1

 Selected without clearly defined sampling frame or with extensive inclusion/exclusion criteria

0

Source of controls

 

 Population or community based

2

 Both population-based and hospital-based/healthy volunteers/blood donors

1.5

 Hospital-based controls without gastric cancer

1

 Cancer-free controls without total description

0.5

 Not described

0

Ascertainment of gastric cancer

 

 Histologically or pathologically confirmed

2

 Diagnosis of gastric cancer by patient medical record

1

 Not described

0

Sample size

 

 >1000

2

 200-1000

1

 <200

0

Quality control of genotyping methods

 

 Clearly described a different genotyping assay to confirm the data

1

 Not described

0

Hardy-Weinberg equilibrium

 

 Hardy-Weinberg equilibrium in controls

1

 Hardy-Weinberg disequilibrium in controls

0.5

 No checking for Hardy-Weinberg disequilibrium

0