Table 3 Meta-analysis of the XPC polymorphisms and gastric cancer risk
From: Current evidences on XPC polymorphisms and gastric cancer susceptibility: a meta-analysis
Comparison | Population | No. of studies | Test of association | Mode | Test of heterogeneity | ||||
|---|---|---|---|---|---|---|---|---|---|
|  |  |  | OR | 95% CI | P Value |  | χ 2 | P Q Value | I 2 |
Lys939Gln | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Gln/Gln vs. Lys/lys | Overall | 5 | 1.123 | 0.881-1.431 | 0.349 | F | 2.69 | 0.612 | 0.0 |
| Â | Caucasian | 2 | 1.016 | 0.490-2.109 | 0.965 | F | 2.31 | 0.128 | 46.8 |
| Â | Asian | 3 | 1.140 | 0.857-1.516 | 0.368 | F | 0.34 | 0.843 | 0.0 |
| Â | PB | 2 | 1.260 | 0.877-1.810 | 0.212 | F | 0.24 | 0.623 | 0.0 |
| Â | HB | 3 | 1.026 | 0.741-1.420 | 0.879 | F | 1.76 | 0.414 | 0.0 |
| Â | High quality | 3 | 1.179 | 0.860-1.616 | 0.308 | F | 0.75 | 0.686 | 0.0 |
| Â | Low quality | 2 | 1.048 | 0.718-1.530 | 0.807 | F | 1.71 | 0.191 | 41.6 |
Gln/Lys vs. Lys/lys | Overall | 5 | 1.083 | 0.917-1.277 | 0.347 | F | 1.21 | 0.876 | 0.0 |
| Â | Caucasian | 2 | 0.993 | 0.689-1.432 | 0.972 | F | 0.87 | 0.352 | 0.0 |
| Â | Asian | 3 | 1.107 | 0.919-1.332 | 0.284 | F | 0.08 | 0.962 | 0.0 |
| Â | PB | 2 | 1.026 | 0.795-1.324 | 0.846 | F | 0.64 | 0.424 | 0.0 |
| Â | HB | 3 | 1.126 | 0.906-1.400 | 0.285 | F | 0.27 | 0.872 | 0.0 |
| Â | High quality | 3 | 1.062 | 0.855-1.319 | 0.587 | F | 0.90 | 0.639 | 0.0 |
| Â | Low quality | 2 | 1.112 | 0.861-1.437 | 0.417 | F | 0.24 | 0.628 | 0.0 |
Gln/Gln + Gln/Lys vs. Lys/lys | Overall | 5 | 1.092 | 0.933-1.277 | 0.273 | F | 0.24 | 0.994 | 0.0 |
| Â | Caucasian | 2 | 1.015 | 0.720-1.430 | 0.933 | F | 0.01 | 0.906 | 0.0 |
| Â | Asian | 3 | 1.113 | 0.933-1.327 | 0.235 | F | 0.00 | 0.998 | 0.0 |
| Â | PB | 2 | 1.076 | 0.846-1.369 | 0.551 | F | 0.18 | 0.667 | 0.0 |
| Â | HB | 3 | 1.103 | 0.897-1.356 | 0.351 | F | 0.03 | 0.986 | 0.0 |
| Â | High quality | 3 | 1.087 | 0.886-1.333 | 0.424 | F | 0.21 | 0.900 | 0.0 |
| Â | Low quality | 2 | 1.098 | 0.860-1.401 | 0.453 | F | 0.02 | 0.881 | 0.0 |
Gln/Gln vs. Gln/Lys + Lys/lys | Overall | 5 | 1.046 | 0.838-1.307 | 0.691 | F | 6.57 | 0.160 | 39.2 |
| Â | Caucasian | 2 | 0.921 | 0.344-2.468 | 0.870 | F | 5.98 | 0.114 | 43.3 |
| Â | Asian | 3 | 1.083 | 0.829-1.417 | 0.558 | F | 0.47 | 0.791 | 0.0 |
| Â | PB | 2 | 1.253 | 0.896-1.751 | 0.187 | F | 0.77 | 0.381 | 0.0 |
| Â | HB | 3 | 0.914 | 0.680-1.229 | 0.552 | F | 3.90 | 0.142 | 48.8 |
| Â | High quality | 3 | 1.157 | 0.862-1.553 | 0.331 | F | 1.66 | 0.435 | 0.0 |
| Â | Low quality | 2 | 0.828 | 0.400-1.712 | 0.610 | F | 3.90 | 0.148 | 44.3 |
Ala499Val | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Val/Val vs. Ala/Ala | Asian | 3 | 0.861 | 0.632-1.172 | 0.341 | F | 0.57 | 0.754 | 0.0 |
Val/Ala vs. Ala/Ala | Asian | 3 | 0.815 | 0.611-1.089 | 0.167 | F | 4.72 | 0.194 | 37.6 |
Val/Val + Val/Ala vs. Ala/Ala | Asian | 3 | 0.823 | 0.630-1.076 | 0.155 | F | 4.49 | 0.106 | 35.5 |
Val/Val vs. Val/Ala + Ala/Ala | Asian | 3 | 0.947 | 0.703-1.274 | 0.717 | F | 0.04 | 0.981 | 0.0 |
PAT−/+ |  |  |  |  |  |  |  |  |  |
+/+vs. −/− | Overall | 2 | 1.035 | 0.763-1.404 | 0.825 | F | 0.12 | 0.726 | 0.0 |
+/− vs. −/− | Overall | 2 | 0.855 | 0.681-1.073 | 0.176 | F | 0.00 | 0.975 | 0.0 |
(+/+) + (+/−) vs. (−/−) | Overall | 2 | 0.896 | 0.724-1.111 | 0.317 | F | 0.05 | 0.830 | 0.0 |
(+/+) vs. (+/−) + (−/−) | Overall | 2 | 1.141 | 0.871-1.495 | 0.338 | F | 0.20 | 0.652 | 0.0 |