Figure 2From: Berberine inhibits the expression of hypoxia induction factor-1alpha and increases the radiosensitivity of prostate cancerBerberine inhibits the expression of HIF-1α and VEGF in LNCaP and DU-145 cells. (A) hypoxia stimulated HIF-1α and VEGF expression in LNCaP and DU-145 cells. (B) IR stimulated HIF-1α and VEGF expression in LNCaP and DU-145 cells. (C) The expression of HIF-1α and VEGF was stimulated in hypoxia conditions and inhibited by berberine in LNCaP and DU-145 cells. (D) The expression of HIF-1α and VEGF was stimulated after IR and inhibited by berberine in LNCaP and DU-145 cells. β-actin was loading control. Ber: berberine.Back to article page