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Figure 5 | Diagnostic Pathology

Figure 5

From: Exploring the spatial dimension of estrogen and progesterone signaling: detection of nuclear labeling in lobular epithelial cells in normal mammary glands adjacent to breast cancer

Figure 5

Connecting data points with regions of interest for individual assessment of lobules. Image analysis approaches connecting data points with individual automatically detected regions of interest enable individual assessment of lobules, pattern detection and quality control. A Overview on analysis results of six cases stained for ER. Every dot reflects the ER positivity ratio in an individual lobule. The spatial distribution of lobules, their predominant staining behavior and the occurrence of outliers is visible at a glance and can be connected with the corresponding upsampled images. B Per-case view. Each dot represents one lobule in the respective case. The horizontal axis shows distance to tumor, the vertical axis shows positive percentage. The blue lines are regression lines.

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