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Table 1 Gender, age and detection of anti- P. aeruginosa IgG in patients with cystic fibrosis and in healthy controls

From: Assessment of IgG antibodies to Pseudomonas aeruginosa in patients with cystic fibrosis by an enzyme-linked immunosorbent assay (ELISA)

Parameters

Subject groups

CF chronic infection

CF intermittent colonization

CF free of infection

CF never colonized

Healthy controls

Number of subjects

31

24

27

35

53

Gender (M/F)

17/14

16/8

8/19

22/13

32/21

Median age - years (range)

14.7 (3 - 30)

9.0 (1.6 - 16)

8.2 (3 - 25)

3.0 (0.16 - 26)

9.7 (0.16 - 30)

% IgG seropositivity [C.I. 95%]

96.8 (81.5 - 99.8)

33.3 (16.4 - 55.3)

11.1 (2.9 - 30.3)

2.9 (0.2 - 16.6)

1.89 (0.1 - 11.4)

  1. The rate of IgG seropositivity in patients chronically infected was significantly higher than those found in the other CF groups and in the healthy control group (p < 0.0001). The rate of IgG seropositivity in intermittent colonized patients was significantly higher than those found in CF patients never colonized and in the healthy controls (p < 0.001).