Table 2 Multivariate analysis of the associations of prognosis with various clinicopathologic parameters and miR-130b expression in HCC patients

Features

HR

95% CI

P value

HR

95% CI

P value

Age

0.981

0.378-1.467

0.41

0.827

0.461-1.251

0.39

Gender

1.091

0.672-1.871

0.56

0.914

0.671-1.889

0.52

HBsAg

1.671

0.871-4.778

0.12

2.121

0.871-5.113

0.14

AFP level

2.119

0.981-5.889

0.11

3.671

0.367-12.112

0.23

Tumor size

3.121

0.478-7.889

0.34

4.116

0.781-11.234

0.31

Histologic grade

4.891

2.113-5.991

0.04

5.995

3.467-8.114

0.01

Tumor number

2.997

0.912-3.091

0.13

3.111

0.872-9.112

0.09

Vein invasion

1.982

0.891-1.971

0.09

2.891

0.781-5.997

0.08

TNM stage

2.131

1.091-6.901

0.009

4.121

1.341-7.113

0.007

miR-130b expression

2.523

1.024-7.901

0.011

4.003

1.578-7.889

0.005