Table 1 Literature review of LGFMS of children (≦15 y. o.)

1

10

M

back

subcutis

FUS gene rearrangement (+) by FISH

pleomorphism (+)

[1]

2

8

M

pelvis

subfascial

φ80mm

(−)

local recurrence and intra abdominal meta 8 mos later

[6]

3

14

M

brachium

subfascial

φ50mm

(-)

[6]

4

14

M

brachium

subfascial

φ30mm

FUS gene rearrangement (+) by FISH

[6]

5

6

M

Lower leg

subcutis

φ10mm

EWSR1 (Ex9)/ CREB3L1 (Ex5) fusion gene by RT-PCR

(-)

[5]

6

13

M

popliteal fossa

deep

FUS/ CREB3L1 fusion gene by array-CGH

(-)

[12]

7

3

M

thigh

subcutis

17 × 16 × 12 mm

FUS gene rearrangement (+) by FISH and

unusual histology+

recurrence 1 year later

[2]

other chromosomal translocations (7q34, 10q11.2, 16p11.2)

calponin (+)

8

5

M

buttock

subcutis

29 × 17 × 25 mm

FUS gene rearrangement (+) by FISH

(+)

[7]

9

6

F

inguinal area

φ35mm

recurrence 5 times, meta for lung 39 years later

[19]

10

9

M

neck

recurrence 7 times, meta 16 years later

[19]

11

6

M

deltoid

φ33mm

(-)

[19]

12

10

F

leg

with giant rosettes

[20]

13

13

F

back

(-) at 36mos

[20]

14

1.8

M

cheek

φ80mm

(-) 6mo

[4]

15

13

F

arm

φ30mm

FUS (Ex6)/ CREB3L2 (Ex5) fusion gene by RT-PCR

(-) at 34mos

[21]

16

11

M

axilla

φ60mm

FUS (Ex6)/ CREB3L2 (Ex5) fusion gene by RT-PCR

[21]

17

15

M

thorax

φ30mm

FUS (Ex6)/ CREB3L1 (Ex5) fusion gene by RT-PCR

[21]

18

13

M

foot

φ60mm

FUS (Ex6)/ CREB3L2 (Ex5) fusion gene by RT-PCR

pleural metastasis at 180, 186, and 203mos,

[21]

pleuropulmonary metastasis at 228 mos

19

13

F

abdominal wall

intramuscular

FUS (Ex6)/ CREB3L2 (Ex5) fusion gene by RT-PCR

[13]

20

2

F

groin/vulva

superficial

φ20mm

(-) at 84mos

[22]

21

3

F

knee/popliteal fossa

superficial

φ42mm

(-) at 60mos

[22]

22

5

M

knee

superficial

φ40mm

(-) at 48mos

[22]

23

6

M

superficial

φ20mm

lost to follow up

[22]

24

8

M

back

superficial

φ30mm

local recurrence at 16mos, then lost to follow up

[22]

25

10

F

lower leg

superficial

φ16mm

(-) at 48mos

[22]

26

13

M

fore arm

superficial

(-) at 60mos

[22]

27

13

F

thigh

FUS (Ex6)-insertion-CREB3L2 (Ex5) fusion gene by RT-PCR

local recurrence at 156, 192, 228, 252, 264,

[23]

and 276 mos

28

12

F

buttock

φ30mm

FUS (Ex6)/ CREB3L2 (Ex5) fusion gene by RT-PCR

lost to follow up

[23]

29

12

M

foot

φ30mm

FUS (Ex6)/ CREB3L2 (Ex5) fusion gene by RT-PCR

local recurrence at 19mos

[23]

30

4

M

paravertebral

90 × 80 × 60 mm

with giant rosettes

local recurrence at 3mos

[24]

31

13

M

buttock

superficial

local recurrence at 24, 36, 60mos

[25]

32

11

F

shoulder

deep

φ45mm

(-) 34mos

[25]

33

14

F

inflaclavicular

φ30mm

(-) 58mos

[26]

34

4

M

thigh

φ30mm

local recurrence at 6, 36, and 84mos

[27]

lung metastasis at 36, 84, and 98mos

this case

5

M

Lower leg

subfascial

φ26mm

FUS (Ex6)/ CREB3L2 (Ex5) fusion gene by RT-PCR

(-) at 4 mos