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Table 2 Available data of the animals, histological classification of the canine gastric tissues and main immunohistochemical findings

From: An immunohistochemical study of canine spontaneous gastric polyps

Case Breed Gender/Age (years) Histological diagnosis Helicobacterspp. COX-2 KI-67 (%) p53 CDX2
SE DG
1 Rottweiler M/12 Hyperplastic polyp +++2 >75%/+++ >75%/ +++ 36,12,3 - -
2 Irish Setter F/12 Hyperplastic polyp +++2 >75%/+++ >75%/+++ 31,42,3 - -
3 Poodle F/12 Hyperplastic polyp +++2 >75%/ +++ >75%/+++ 32,12,3 - -
4 Argentine Mastiff F/9 Hyperplastic polyp ++2 >75%/+++ >75%/ +++ 28,92,3 - -
5 Rottweiler F/14 Hyperplastic polyp +2 >75%/+++ >75%/+++ 30,92,3 - -
6 Mixed breed F/16 Hyperplastic polyp ++2 >75%/+++ >75%/+++ 16,72,3 - -
7 Poodle M/13 Inflammatory polyp ++2 >75%/+++ >75%/+++ 31,52,3 - -
8 German Shepherd M/9 Inflammatory polyp ++2 >75%/+++ >75%/+++ 10,82 - -
9 Boxer M/10 Hyperplastic polyp +1 >75%/+++ >75%/+++ 4,62 - -
10 Mixed breed M/2 NGM 0 >75%/+++ >75%/+ 18,32 - -
11 Poodle cross F/15 NGM 0 >75%/+++ >75%/++ 23,62 - -
12 Boxer M/4 NGM 0 >75%/+++ >75%/+ 15,62 - -
13 Mixed breed M/8 NGM 0 >75%/+++ >75%/++ 22,82 - -
  1. M male, F female.
  2. COX-2: SE, surface epithelium; DG, deeper glands. >75% of immunopositive cells, + weak, ++ moderate, +++ strong intensity.
  3. Helicobacter spp.: + few; ++ moderate number; +++ large number of organisms. The bacteria location 0, absent; 1 = on mucosal surface and within gastric pits; 2 = 1+ lumen of the gastric glands; KI-67: zone 2, isthmus and zone 3, gland base; p53 and CDX2: −, negative.