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Table 2 Clinical characteristics

From: Automated quantification of Ki-67 proliferative index of excised neuroendocrine tumors of the lung

 

All tumors

TC

AC

LCNEC

n

55

39

7

9

Mean age ± SD (yrs)

60.8 ± 11.2

61.8 ± 12.6

61.5 ± 6.5

55.2 ± 5.5

Range (yrs)

33.6-79.4

33.6-79.4

51.1-73.4

47.5-61.6

Sex

    

Females

41 (75%)

31 (80%)

5 (71%)

5 (56%)

Males

14 (25%)

8 (20%)

2 (29%)

4 (44%)

Race ‡

    

White

41

32

6

3

Black

12

5

1

6

Other

2

2

0

0

Smoking hx †

    

Smoker

27 (59%)

16 (50%)

2 (40%)

9 (100%)

Nonsmoker

19 (41%)

16 (50%)

3 (60%)

0 (0%)

Data unavailable

9

7

2

0

Location

    

Central

46 (84%)

34 (87%)

6 (86%)

6 (67%)

Peripheral

9 (18%)

5 (13%)

1 (14%)

3 (33%)

Mean tumor size ± SD (cm)

2.2 ± 1.5

2.1 ± 1.5

2.7 ± 1.9

2.8 ± 1.2

Range (cm)

0.2-6.9

0.2-6.9

0.7-5.5

0.4-4.5

Tumor stage (T)

    

T1a

26

19

3

4

T1b

10

8

2

0

T2a

16

10

1

5

T2b

1

1

0

0

T3

2

1

1

0

Nodal stage (N)

    

Nx

1

0

0

1

N0

46

35

5

6

N1

5

3

1

1

N2

3

1

1

1

Metastatic stage (M)

    

M0

53

39

6

8

M1

2

0

1

1

Procedure

    

Other

2

1

1

0

Wedge

14

5

2

7

Segmentectomy

2

2

0

0

Lobectomy

30

25

4

1

Bilobectomy

4

4

0

0

Pneumonectomy

3

2

0

1

  1. AC = atypical carcinoid; TC = typical carcinoid; LCNEC = large cell neuroendocrine carcinoma.
  2. ‡p = 0.0005 Fisher's exact test, LCNEC vs. TC and AC, Whites vs. Blacks.
  3. †p = .005, LCNEC vs. AC and TC.