|
Clinicopathological features
|
Case
|
Nucleolin expression frequency (n,%)
|
P
|
|---|
|
High
|
Low
|
|---|
|
Age (years)
| | | | |
|
≤50
|
72
|
40 (55.56)
|
32 (44.44)
|
NS
|
|
>50
|
58
|
28 (48.28)
|
20 (51.72)
|
|
Gender
| | | | |
|
Male
|
96
|
58 (60.42)
|
42 (39.58)
|
NS
|
|
Female
|
34
|
20 (58.82)
|
14 (41.18)
|
|
Serum AFP
| | | | |
|
Positive
|
72
|
58 (80.56)
|
14 (19.44)
|
0.008
|
|
Negative
|
58
|
20 (34.48)
|
38 (65.52)
|
|
Tumor stage
| | | | |
|
T1
|
23
|
0 (0)
|
23 (100.00)
|
0.001
|
|
T2
|
40
|
23 (57.50)
|
17 (42.50)
|
|
T3
|
52
|
40 (76.92)
|
12 (23.08)
|
|
T4
|
15
|
15 (100.00)
|
0 (0)
|
|
Tumor grade
| | | | |
|
G1
|
31
|
12 (38.71)
|
19 (61.29)
|
0.02
|
|
G2
|
76
|
48 (63.16)
|
28 (36.84)
|
|
G3
|
23
|
18 (78.26)
|
5 (21.74)
|
|
Growth pattern
| | | | |
|
Trabecular
|
101
|
59 (58.42)
|
42 (41.58)
|
NS
|
|
Nontrabecular
|
29
|
19 (65.52)
|
10 (34.48)
|
|
Cirrhosis
| | | | |
|
Yes
|
86
|
50 (58.14)
|
36 (41.86)
|
NS
|
|
No
|
44
|
28 (63.64)
|
16 (36.46)
|
|
Underlying liver disease
| | | | |
|
Alcoholic
|
25
|
10 (40.00)
|
15 (60.00)
|
NS
|
|
Hepatitis B
|
49
|
28 (57.14)
|
21 (42.86)
|
|
Hepatitis C
|
35
|
28 (80.00)
|
7 (20.00)
|
|
Unknown
|
21
|
12 (57.14)
|
9 (42.86)
|
- Note: `NS' refers to the differences among groups have no statistical significance.
