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Table 3 Subgroup analysis of the MMP-1 SNP rs5854 regarding with the period before aseptic loosening happens

From: Genetic susceptibility to total hip arthroplasty failure: a case-control study on the influence of MMP 1 gene polymorphism

Period (year)

Allele (%)

CC

CT

TT

CT + TT

CT + CC

TT

C

T

0-5

5

8

4

12

13

4

52.9

47.1

5-10

31

10

5

15

41

5

78.3

21.7

ORa (95% CI)

/

/

0.23 (0.12 to 1.16)

0.15 (0.08 to 0.43)

/

0.37 (0.09 to 1.47)

/

0.28 (0.10 to 0.40)

Pa

/

/

0.0750

0.0025

/

0.1762

/

< 0.0001

  1. aORs and 95% CIs were estimated using multiple logistic regression analyses and adjusted for age, gender and BMI.