From: Down-regulated miR-22 as predictive biomarkers for prognosis of epithelial ovarian cancer
Variables | n | miR-22 expression level | P value | |
---|---|---|---|---|
Low | High | |||
Age, y | ||||
<55 | 46 | 16 | 30 | 0.29 |
?55 | 63 | 39 | 24 | |
FIGO stage | ||||
I-II | 61 | 17 | 44 | 0.006 |
III-IV | 48 | 38 | 10 | |
Histology | ||||
Serous | 71 | 34 | 37 | 0.65 |
Nonserous | 38 | 21 | 17 | |
Residual tumor size (cm) | ||||
<1.0 | 79 | 37 | 42 | 0.09 |
?1.0 | 30 | 18 | 12 | |
Grade | ||||
Well | 31 | 5 | 26 | 0.03 |
Moderate | 43 | 23 | 20 | |
Poor | 35 | 27 | 8 | |
Lymph node metastases | ||||
Negative | 81 | 34 | 47 | 0.01 |
Positive | 28 | 21 | 7 | |
Serum CA125 | ||||
<319 | 56 | 24 | 32 | 0.12 |
?319 | 53 | 31 | 22 |