Figure 3

Photos of tubules in patients of LBW-related nephropathy and patients with mtDNA mutation; (A)-(F): Masson's Trichrome stain, (G) and (H): electron microscopy (original magnification: × 3000). GESCs are present in collecting ducts or distal tubules of LBW 1 (A), LBW 2 (B), LBW 3 (C), LBW 4 (D), Mt 1 (E), and Mt 2 (F). In LBW 4 (G), the number of mitochondria with morphological abnormalities is increased in the collecting duct. One nucleus appears to be condensed. In Mt 2 (H), increased mitochondria are also observed in the cytoplasm of collecting duct.