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Table 4 Stratification analysis of IL-22 -429 C/T polymorphisms in ulcerative colitis cases

From: Association of the interleukin-22 genetic polymorphisms with ulcerative colitis

 

Cases (n = 180)

CC

CT

TT

n (%)

OR (95% CI)

P

n (%)

OR (95% CI)

P

n (%)

OR (95% CI)

P

Clinical type

180

57(31.7)

1(Reference)

 

70(38.9)

1(Reference)

 

53(29.4)

1(Reference)

 

One episode

16

5(31.2)

0.99(0.35,2.81)

0.98

7(43.8)

1.13(0.44,2.85)

0.80

4(25.0)

0.85(0.27,2.65)

0.78

Relapsing

70

24(34.3)

1.08(0.62,1.88)

0.78

26(37.1)

0.96(0.56,1.62)

0.87

20(28.6)

0.97(0.54,1.74)

0.92

Continuous

94

28(29.8)

0.94(0.56,1.58)

0.82

37(39.4)

1.01(0.63,1.62)

0.96

29(30.8)

1.05(0.63,1.76)

0.86

Location

180

57(31.7)

1(Reference)

 

70(38.9)

1(Reference)

 

53(29.4)

1(Reference)

 

Proctitis (E1)

73

24(32.9)

1.04(0.60,1.80)

0.89

27(37.0)

0.95(0.57,1.60)

0.85

22(30.1)

1.02(0.58,1.80)

0.94

Left side (E2)

64

20(31.3)

0.99(0.55,1.77)

0.97

26(40.6)

1.05(0.61,1.78)

0.87

18(28.1)

0.96(0.52,1.75)

0.88

Extensive (E3)

43

13(30.2)

0.96(0.48,1.90)

0.89

17(39.6)

1.02(0.54,1.90)

0.96

13(30.2)

1.03(0.51,2.05)

0.94

Disease severity

180

57(31.7)

1(Reference)

 

70(38.9)

1(Reference)

 

53(29.4)

1(Reference)

 

Mild

76

25(32.9)

1.04(0.61,1.79)

0.89

28(36.8)

0.95(0.57,1.58)

0.84

23(30.3)

1.03(0.59,1.80)

0.92

Moderate

95

29(30.5)

0.96(0.58,1.61)

0.89

38(40.0)

1.03(0.65,1.64)

0.91

28(29.5)

1.00(0.59,1.68)

0.99

Severe

9

3(33.3)

1.05(0.28,4.02)

0.94

4(44.5)

1.14(0.34,3.83)

0.83

2(22.2)

0.76(0.16,3.60)

0.72

  1. Abbreviations: OR odds ratio, CI confidence interval.