From: Association of the interleukin-22 genetic polymorphisms with ulcerative colitis
 | Cases (n = 180) | CC | CT | TT | ||||||
---|---|---|---|---|---|---|---|---|---|---|
n (%) | OR (95% CI) | P | n (%) | OR (95% CI) | P | n (%) | OR (95% CI) | P | ||
Clinical type | 180 | 57(31.7) | 1(Reference) | Â | 70(38.9) | 1(Reference) | Â | 53(29.4) | 1(Reference) | Â |
One episode | 16 | 5(31.2) | 0.99(0.35,2.81) | 0.98 | 7(43.8) | 1.13(0.44,2.85) | 0.80 | 4(25.0) | 0.85(0.27,2.65) | 0.78 |
Relapsing | 70 | 24(34.3) | 1.08(0.62,1.88) | 0.78 | 26(37.1) | 0.96(0.56,1.62) | 0.87 | 20(28.6) | 0.97(0.54,1.74) | 0.92 |
Continuous | 94 | 28(29.8) | 0.94(0.56,1.58) | 0.82 | 37(39.4) | 1.01(0.63,1.62) | 0.96 | 29(30.8) | 1.05(0.63,1.76) | 0.86 |
Location | 180 | 57(31.7) | 1(Reference) | Â | 70(38.9) | 1(Reference) | Â | 53(29.4) | 1(Reference) | Â |
Proctitis (E1) | 73 | 24(32.9) | 1.04(0.60,1.80) | 0.89 | 27(37.0) | 0.95(0.57,1.60) | 0.85 | 22(30.1) | 1.02(0.58,1.80) | 0.94 |
Left side (E2) | 64 | 20(31.3) | 0.99(0.55,1.77) | 0.97 | 26(40.6) | 1.05(0.61,1.78) | 0.87 | 18(28.1) | 0.96(0.52,1.75) | 0.88 |
Extensive (E3) | 43 | 13(30.2) | 0.96(0.48,1.90) | 0.89 | 17(39.6) | 1.02(0.54,1.90) | 0.96 | 13(30.2) | 1.03(0.51,2.05) | 0.94 |
Disease severity | 180 | 57(31.7) | 1(Reference) | Â | 70(38.9) | 1(Reference) | Â | 53(29.4) | 1(Reference) | Â |
Mild | 76 | 25(32.9) | 1.04(0.61,1.79) | 0.89 | 28(36.8) | 0.95(0.57,1.58) | 0.84 | 23(30.3) | 1.03(0.59,1.80) | 0.92 |
Moderate | 95 | 29(30.5) | 0.96(0.58,1.61) | 0.89 | 38(40.0) | 1.03(0.65,1.64) | 0.91 | 28(29.5) | 1.00(0.59,1.68) | 0.99 |
Severe | 9 | 3(33.3) | 1.05(0.28,4.02) | 0.94 | 4(44.5) | 1.14(0.34,3.83) | 0.83 | 2(22.2) | 0.76(0.16,3.60) | 0.72 |