Table 6 Stratification analysis of IL-22 +1995 A/C polymorphisms in ulcerative colitis cases
From: Association of the interleukin-22 genetic polymorphisms with ulcerative colitis
| Â | Cases (n = 180) | AA | AC | CC | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
n (%) | OR (95% CI) | P | n (%) | OR (95% CI) | P | n (%) | OR (95% CI) | P | ||
Clinical type | 180 | 76(42.2) | 1(Reference) | Â | 65(36.1) | 1(Reference) | Â | 39(21.7) | 1(Reference) | Â |
One episode | 16 | 7(43.8) | 1.04(0.41,2.62) | 0.94 | 6(37.5) | 1.04(0.39,2.77) | 0.94 | 3(18.7) | 0.87(0.24,3.12) | 0.83 |
Relapsing | 70 | 29(41.4) | 0.98(0.59,1.63) | 0.94 | 25(35.7) | 0.99(0.58,1.69) | 0.97 | 16(22.9) | 1.06(0.55,2.01) | 0.87 |
Continuous | 94 | 40(42.6) | 1.01(0.64,1.59) | 0.97 | 34(36.2) | 1.00(0.62,1.63) | 0.99 | 20(21.2) | 0.98(0.54,1.78) | 0.95 |
Location | 180 | 76(42.2) | 1(Reference) | Â | 65(36.1) | 1(Reference) | Â | 39(21.7) | 1(Reference) | Â |
Proctitis (E1) | 73 | 31(42.5) | 1.01(0.61,1.66) | 0.98 | 26(35.6) | 0.99(0.58,1.68) | 0.96 | 16(21.9) | 1.01(0.53,1.92) | 0.97 |
Left side (E2) | 64 | 26(40.6) | 0.96(0.57,1.63) | 0.89 | 24(37.5) | 1.04(0.60,1.80) | 0.89 | 14(21.9) | 1.01(0.52,1.98) | 0.98 |
Extensive (E3) | 43 | 19(44.2) | 1.05(0.57,1.91) | 0.88 | 15(34.9) | 0.97(0.50,1.86) | 0.92 | 9(20.9) | 0.97(0.44,2.15) | 0.93 |
Disease severity | 180 | 76(42.2) | 1(Reference) | Â | 65(36.1) | 1(Reference) | Â | 39(21.7) | 1(Reference) | Â |
Mild | 76 | 33(43.4) | 1.03(0.63,1.68) | 0.91 | 27(35.5) | 0.98(0.58,1.66) | 0.95 | 16(21.1) | 0.97(0.51,1.84) | 0.93 |
Moderate | 95 | 39(41.1) | 0.97(0.61,1.54) | 0.91 | 35(36.8) | 1.02(0.63,1.65) | 0.94 | 21(22.1) | 1.02(0.57,1.83) | 0.95 |
Severe | 9 | 4(44.5) | 1.05(0.32,3.52) | 0.93 | 3(33.3) | 0.92(0.24,3.52) | 0.91 | 2(22.2) | 1.03(0.21,4.93) | 0.98 |