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Table 2 Clinical features of AKU patients

From: Diagnosis of secondary amyloidosis in alkaptonuria

Patient #

Date of selection (month/year)

Peripheral neuropathy

Orthostatic hypotension

Ventricular and atrial dilatation

chronic bacterial infection

Spondylarthropathy

Glossomegaly

Surgery

1

08/2011

y

y

y

n

y

y

Knee (r), shoulder (r) and hip (l) arthroplasty

2

10/2009

y

y

n

y

y

n

Knee (r, l), shoulder (r) and hip (r) arthroplasty

3

03/2012

n

y

n

n

y

n

Meniscus (r) surgical repair

4

04/2012

y

y

n

n

n

n

None

5

11/2012

y

y

n

y

y

n

Knee (l), and hip (l) arthroplasty

6

01/2013

y

n

n

y

y

n

Knee (r) arthroplasty

7

05/2012

n

y

n

n

n

n

None

8

02/2012

y

y

y

n

y

n

Knee (l) arthroplasty

9

03/2013

y

n

y

y

y

y

Knee (r) and tendon ankle fracture (l)

10

11/2011

y

y

n

n

y

y

Knee (r), and hip (l) arthroplasty

  1. No patient was receiving immunosuppressive or chemotherapy treatment. y = yes; n = no; r = right; l = left.