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Table 3 Risk of death during follow-up according to clinicopathological factors in the entire cohort

From: Incident urothelial cancer in the Malmö Diet and Cancer Study: cohort characteristics and further validation of ezrin as a prognostic biomarker

Factor

Unadjusted

Adjusted

 

n (events)

HR (95% CI)

n (events)

HR (95% CI)

Age

    

Continuous

355 (166)

1.06 (1.04-1.09)

342

1.05 (1.03-1.08)

Gender

    

Female

109 (42)

1.00

103 (38)

1.00

Male

246 (124)

1.30 (0.92-1.85)

239 (122)

1.17 (0.81-1.70)

Stage

    

Ta

163 (63)

1.00

163 (63)

1.00

T1

97 (42)

1.61 (1.09-2.39)

97 (42)

1.16 (0.73-1.82)

T2

64 (48)

3.97 (2.71-5.82)

64 (48)

2.60 (1.60-4.23)

T3-4

6 (5)

13.13 (5.16-33.39)

6 (5)

7.81 (2.99-20.41)

Tis

12 (2)

0.38 (0.09-1.56)

12 (2)

0.42 (0.10-1.71)

Grade

    

Low

183 (65)

1.00

182 (64)

1.00

High

150 (96)

2.54 (1.85-3.48)

148 (94)

1.73 (1.14-2.62)

Location

    

Bladder

335 (158)

1.00

327 (153)

1.00

Other

15 (7)

0.84 (0.39-1.79)

15 (7)

0.87 (0.38-1.95)

Smoking

    

Regularly

125 (64)

1.00

120 (61)

1.00

Occasionally

23 (9)

0.63 (0.31-1.26)

23 (9)

0.69 (0.34-1.42)

Former

155 (71)

0.84 (0.60-1.18)

150 (71)

0.87 (0.61-1.25)

Never

52 (22)

0.81 (0.50-1.31)

49 (19)

0.86 (0.50-1.48)