Table 1 Correlation between miR-224 expression and different clinicopathological features in non-small cell lung cancer

Age

<60

58

34 (58.6%)

24 (41.4%)

0.094

≥60

57

24 (42.1%)

33 (57.9%)

Gender

Male

77

40 (51.9%)

37 (48.1%)

0.695

Female

38

18 (47.4%)

20 (52.6%)

Smoking status

Smoking

68

38 (55.9%)

30 (44.1%)

0.591

No smoking

47

20 (42.6%)

27 (57.4%)

Smoking intensity (for smokers)

<30 pack years

38

17 (44.7%)

21 (55.3%)

0.484

≥30 pack years

30

17 (56.7%)

13 (43.3%)

Occupational exposure

Yes

32

14 (43.8%)

18 (56.2%)

0.411

No

83

44 (53.0%)

39 (47.0%)

Histological type

Squamous cell carcinoma

40

23 (57.5%)

17 (42.5%)

Adenocarcinoma

61

26 (42.6%)

35 (57.4%)

0.186

Others

14

9 (64.3%)

5 (35.7%)

Histological grade

G1 + G2

61

27 (44.3%)

34 (55.7%)

0.192

G3

54

31 (57.4%)

23 (42.6%)

T classification

T₁₊₂

77

36 (46.8%)

41 (53.2%)

0.323

T₃

38

22 (57.9%)

16 (42.1%)

N classification

Positive

80

48 (60.0%)

32 (40.0%)

0.002

Negative

35

10 (28.6%)

25 (71.4%)

TNM stage

I + II

69

25 (36.2%)

44 (63.8%)

<0.001

III

46

33 (71.7%)

13 (28.3%)